Pregnancy and the Risk of Relapse in Patients Diagnosed with Hodgkin Lymphoma

Pregnancy and the Risk of Relapse in Patients Diagnosed with Hodgkin Lymphoma

Weibull, CE, (2016) Journal of Clinical Oncology (Link to abstract)


There is data from the 1950’s to suggest that relapse might be more frequent in women who get pregnant after treatment for Hodgkin Disease. This is a retrospective study using the Swedish healthcare registry. Adult women with Hodgkin’s Disease were followed for relapse and pregnancy. Pregnancy-related relapse was defined as relapse during or within 5 years of pregnancy. They found fewer pregnancy-associated relapses than predicted thereby providing no evidence that pregnancy is a risk factor for relapse of Hodgkin’s Disease.


* Being a registry-based study, there are weaknesses including the fact that some pregnancies may not have been recorded if they occurred out of country or if there was no in-hospital care. However, this study is pretty decent evidence that clinicians should not advise against pregnancy for fear of relapse of Hodgkin Disease.