Review of phase I and II trials for Wilms’ tumour - Can we optimise the search for novel agents?

Review of phase I and II trials for Wilms’ tumour - Can we optimise the search for novel agents?
This is a review of 63 published phase 1 and phase 2 studies (2005-2016) which included patients with relapsed/refractory Wilms Tumors. The authors discuss availability and trial recruitment in WT, poor clinical outcome of patients, poor responses of WT to novel agents to date, and future drug development for these patients.

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