Dose level response rates of mTOR inhibition in tuberous sclerosis complex (TSC) related subependymal giant cell astrocytoma (SEGA)

Dose level response rates of mTOR inhibition in tuberous sclerosis complex (TSC) related subependymal giant cell astrocytoma (SEGA)

Weidman, D. (2015) Pediatric Blood and Cancer (Link to abstract)                        



* Therapeutic dose of mTOR inhibitor is effective in shrinking TSC related SEGAs. Doses less than 2.5 mg/m2 were insufficient to maintain response in this limited series.