Giri S (2015) Blood (Link to abstract)
The NCI database of cancer patient follow up SEER 9 was used to analyze a total of 5776 women with Hodgkin lymphoma followed up for a median duration of 229 months. The authors found an excess risk of breast cancer with diagnosis at a median age of 46 years and a latency of 231 months since HL diagnosis. In contrast the median age for a breast cancer diagnosis in the general population is 61 years (data from the same database). The age-adjusted incidence ratios steadily declined over the study time. The authors speculate that this might be due to advances in radiation techniques (involved field vs. extended field), less radiation, differences in chemotherapies or combinations.
* This report confirms the excess risk of breast cancer in HL survivors and highlights that these women develop breast cancer at an earlier age. The good news is that the age-adjusted incidence declines.